منابع مشابه
Asymptomatic humans transmit dengue virus to mosquitoes.
Three-quarters of the estimated 390 million dengue virus (DENV) infections each year are clinically inapparent. People with inapparent dengue virus infections are generally considered dead-end hosts for transmission because they do not reach sufficiently high viremia levels to infect mosquitoes. Here, we show that, despite their lower average level of viremia, asymptomatic people can be infecti...
متن کاملDengue Emergence and Adaptation to Peridomestic Mosquitoes
Phylogenetic evidence suggests that endemic and epidemic dengue viruses (DENV), transmitted among humans by the anthropophilic mosquitoes Aedes aegypti and Ae. albopictus, emerged when ancestral, sylvatic DENV transmitted among nonhuman primates by sylvatic Aedes mosquitoes adapted to these peridomestic vectors. We tested this hypothesis by retrospectively examining evidence for adaptation of e...
متن کاملGenetic elimination of dengue vector mosquitoes.
An approach based on mosquitoes carrying a conditional dominant lethal gene (release of insects carrying a dominant lethal, RIDL) is being developed to control the transmission of dengue viruses by vector population suppression. A transgenic strain, designated OX3604C, of the major dengue vector, Aedes aegypti, was engineered to have a repressible female-specific flightless phenotype. This stra...
متن کاملReducing Dengue Fever Through Biological Control of Disease Carrier Aedes Mosquitoes (Diptera: Culicidae)
Dengue is an infection that is carried by Aedes mosquitoes (Diptera: Culicidae) and can cause severe disease in peoples living in tropics. It is capable to cause headaches, pain and rash, and in other harsh types, may cause internal bleeding and then mortality of the patient. Currently, there is no vaccine for the treatment of dengue sickness and the most widely used methods for control of dise...
متن کاملAssessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes.
Mosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to control dengue transmission. In order to prepare for open-field testing releases o...
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ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.327.5972.1431-a